Genmab A has an average 1 year price target of $37.33, a downside of -10.21% from Genmab A’s current stock price of $41.58. Arcturus Therapeutics Holdings has an average 1 year price target of $26.00, a downside of -5.69% from Arcturus Therapeutics Holdings’s current stock price of $27.57. Harmony Biosciences Holdings has an average 1 year price target of $60.40, an upside of 91.69% from Harmony Biosciences Holdings’s current stock price of $31.51.

It’s important to note, Enliven doesn’t yet sell a product, so it doesn’t have any sales. The company is also expected to report several more years of losses. Most biotech companies have many drugs simultaneously under development, which provides multiple revenue streams. The safest biotech investments are focused on more than just a few experimental drugs. It’s possible that Intellia could have another clinical program soon.

Rosa discussed the company’s outlook in building its neuroscience platform using thin film electrode technology. PF614 is being developed using Ensysce’s Trypsin Activated Abuse Protection platform. TAAP is designed to be resistant to tampering and abuse and is a “unique chemical modification creating a new generation of opioid pain products,” according to the company.

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Jaimini Desai has been a financial writer and reporter for nearly a decade. He has helped countless investors take profitable rides on some of the hottest growth trends. His previous experience includes writing for Investopedia, Seeking Alpha and MT Newswires. Specifically, INCY is up 13% since mid-March 2020, while the S&P 500 has spiked 83%, and IBB has returned 25%. And since Q2 2020, INCY’s revenues are up 25% and EPS have nearly doubled. This top- and bottom-line growth is expected to continue, with analysts forecasting increases of 14% and 25%, respectively, this fiscal year.

Axsome launched Auvelity in October 2022 as a treatment for major depressive disorder. The drug, also known as AXS-05, is also being evaluated in a late-stage clinical trial targeting Alzheimer’s disease agitation and in a phase 2/3 study as a smoking cessation therapy. But as we’ve discussed, some biotech stocks go bust without getting the chance to sell a product — and it can take a lot of research to pick out the winners from the losers. Below is a list of 10 of the best-performing biotech stocks in the New York Stock Exchange Arca Biotechnology Index. As those examples show, smaller biotech companies often live or die on clinical trial results and FDA approvals. That is, companies like CRISPR lack the resources to get drugs tested and past regulators.

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It ranks fourth behind Amgen , Gilead Sciences and Regeneron Pharmaceuticals . Exelixis is profitable, which enables it to use its fast-growing cash stockpile to enter into new licensing agreements and expand its drug offerings. It licenses from the development-stage biotech company Aurigene the right to develop a promising early-stage cancer drug called XL102.

They’re thematic, diversified, built for long-Best biotech stocks to buy now returns, and they’re right here in our brand new web platform. Any rewards or free trials offered through Gainy’s client referral program are subject to full program terms & conditions. Bite-size important facts and numbers about the markets, the world around us, and what it all means for you, written in simple language with a bit of humor. Discover and automatically rebalance your investments based on your interests, portfolio and goals. We know that traders always need information, so we created FAQ, Knowledge Base, and Blog. FAQ allows users to get any brief details on the market and stocks; any “How to” & “What if” questions are here.

Axsome Therapeutics

The two partners hope to begin a pivotal clinical trial of NTLA-2001 by the end of 2023, pending regulatory feedback. Positive results can cause a rally in a small-cap biotech stock because they suggest the company will get permission to sell its new drug — which can be the first step to becoming a large-cap biotech company. Biotech stocks are publicly traded ownership shares of companies that make medicines, vaccines and other biological products.

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For instance, clinical-stage biotech company Zosano Pharma Corporation filed for Chapter 11 bankruptcy after the FDA rejected a migraine drug delivery patch it had been developing. In 2019, Warren Buffett’s investment firm Berkshire Hathaway purchased biotech stocks for the first time. The firm purchased more than 648,000 shares of Biogen stock, worth $192.4 million. It was the first biotech company Buffett chose to invest in through his decades long history as the Oracle of Omaha.

For every success story like Moderna, there’s a letdown like Calithera Biosciences. With this backdrop, NMTC has hit the scanners of some traders in the stock market today. Monday’s trading volume was significantly higher than average, and one-day price movement was much more robust following the Fox Business spot. A recent milestone to note is NeuroOne’s Evo sEEG Electrode received FDA 510 clearance to market for temporary use. As discussed above, we’re looking for current and future potential catalysts.

It is expected that small private biotech firms will make a comeback in the initial public offering market in the later part of 2023 as the rate of interest rate hikes slows down. However, due to challenging economic conditions, investors are likely to be more selective in their choices and prioritize companies with drugs in human trials. After a successful year in 2021, the number of initial public offerings across all industries took a sharp decline worldwide in the past year. This decline was due to central banks’ implementation of aggressive interest rate hikes to combat inflation, thereby ending the period of easily available and low-cost capital.

• Trading below cash can happen when companies hit a negative newsflow, including worsening macroeconomic outlooks, negative clinical results, layoffs and delays with regulatory agencies.
• The safest biotech investments are focused on more than just a few experimental drugs.
• Companies that only have one major project in the works are far riskier than those with multiple irons in the fire.
• He has helped countless investors take profitable rides on some of the hottest growth trends.
• Through these rights, the company generates and manages carbon credits by utilizing the most technologically advanced, blockchain based platform.

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The biotechnology industry includes companies that develop drugs and diagnostic technologies for the treatment of diseases and medical conditions. These products must go through rigorous, costly, and time-consuming trials before potentially obtaining approval from the U.S. This means that investors may wait for years before knowing whether a drug under development will pay off. The industry includes smaller start-up companies with recent traction as well as large, well-established corporations that aim to develop a range of drugs and technologies. Many biotech companies have shifted their focus entirely or added COVID-19 vaccines and treatments to their product pipeline.

CRISPR Therapeutics (CRSP)

The growth of biopharmaceuticals market is driven by the potential to treat rare diseases, the rising application of biopharmaceuticals in cancer therapeutics, and contract manufacturing of biopharmaceuticals. The biopharmaceuticals market is estimated to grow at a CAGR of 7.3% until 2027. Of the 48 biotech stocks in the index, 13 are covered by Morningstar analysts. To find undervalued biotech stocks, we turned to the Morningstar US Biotechnology Index.

Provide specific products and services to you, such as portfolio management or data aggregation. Moreover, the biotech company’s stock continued to climb sharply throughout the pandemic, gaining over 1,450% between March 2020 and August 2021. Read this easy guide to learn more about stocks and see how you can gain returns on your investment. Dawn Allcot is a full-time freelance writer and content marketing specialist who geeks out about finance, e-commerce, technology, and real estate. Her lengthy list of publishing credits include Bankrate, Lending Tree, and Chase Bank.

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The best biotech companies are well-positioned to deliver tremendous returns over long periods of time, making them well-suited for buy-and-hold investors. The company has already advanced the drug into phase 2 testing in New Zealand and is seeking to move forward with U.S. phase 2 testing. Some are skewed toward large-cap companies, while others specialize in small, early-stage companies.

At the time, the stock may have been worth as much as $267 million, or a 39% return on investment if Buffett sold at the stock’s high point. If you want to diversify your risk, consider investing in a biotech ETF, which is a balanced collection of biotech stocks. At a current price of under $18 per share, Exelixis is at a very attainable entry point for new investors and shows a lot of growth potential. However, it’s worth noting that the price dropped recently when a Phase 3 trial for the company’s renal cell carcinoma treatment was less effective than the company had hoped. BioMarin has recently had a string of good news resulting in the company upgrading its full-year revenue predictions. The $16.87 billion company specializes in pioneering treatments for rare genetic disorders and already has many drugs on the market.

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The company is working on approval for additional indications that could potentially increase the total addressable market for Korlym. For Cushing’s, the drug has been given orphan status that gives it exclusivity until 2037, although it is being challenged by generic drug manufacturers. However, the stock’s outperformance has continued despite this headwind due to its growth and presence in many other large markets. These include cancer, cardiovascular issues, eye disease, inflammation and asthma.

Visit an ETF’s website and check its portfolio or holdings to see what you’d be investing in. Health care spending accounted for 18.3% of U.S. gross domestic product in 2021, the latest year for which data is available. The biotech industry is the cutting edge of the health care sector — it develops new health care products. The investing information provided on this page is for educational purposes only. NerdWallet does not offer advisory or brokerage services, nor does it recommend or advise investors to buy or sell particular stocks, securities or other investments. Reddit penny stocks, cryptocurrency & high risk assets are all the rage in retail trading in April 2021.

Many large-cap biotech companies have several different products on the market that treat different medical conditions. These are subject to capping requirements, with no more than 8% in any one stock. The expense ratio is low at 0.44%, and there are $7.94 billion of assets under management. Consider that the potential for most biotech companies isn’t what their current earnings or valuations are.

In addition, the company is developing other drugs for the treatment of dengue and hepatitis C. As a result, Atea plans to test its lead candidate antiviral in a phase 3 trial by the end of 2022. The trial will recruit at least 1,500 high-risk, non-hospitalized patients with mild or moderate COVID-19, and will test the drug’s impact on all-cause hospitalization or death. They also received one tradeable Contingent Value Right for each share of Celgene, which guarantees future rewards when the combined company meets future regulatory milestones.

The companies listed below have mid- to large market caps, so investors can expect the stock prices to keep rising over time. To determine the most promising biotech stocks, we focused on pure-play biotech companies. We narrowed down our selection to biotech stocks that had the highest upside potential based on average analyst price targets. We have ranked our picks in ascending order of their average upside potential, as of February 24. The biotech sector is also presenting exciting opportunities for investors. Many of the best biotech companies have both strong drug candidate pipelines and winning drugs already on the market.

The company serves wholesalers, retailers, hospitals, clinics, government agencies, and disease control and prevention centers. Despite market volatility, the biotech sector has performed relatively well as a result of breakthrough achievements, advancements in biopharma, and inelastic demand for healthcare products and services. Incyte also received U.S. approval of Pemazyre in cholangiocarcinoma in 2020. “CRISPR/Cas9 works by having CRISPR guide Cas9 to edit, alter, or repair genes. Intellia is utilizing this gene knockout approach to remove unwanted proteins using its proprietary lipid nanoparticle delivery system.